Note: This web page is a part of DTSC's Hazardous Waste Classification training course. 

Acute Dermal Toxicity

Acute Dermal Toxicity is the dose of a substance or mixture of substances, in milligrams per kilogram of test animal body weight, which, when applied continuously to the bare skin for 24 hours, produces death with 14 days in half of a group of 10 or more rabbits.

Illustration of acute dermal toxicity when a substance is applied to the skin of rabbits.

The waste is considered a hazardous waste by dermal toxicity1 if its dermal LD50 is less than 4300 mg/kg.

LD50 < 4300 mg/kg = acute dermal toxicity

References

1 22 CCR Section 66261.24(a)(4)

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